Metabolic Engineering of Glycerol Production in Saccharomyces cerevisiae

Inactivation of TPI1, the Saccharomyces cerevisiae structural gene encoding triose phosphate isomerase, completely eliminates growth on glucose as the sole carbon source. In tpi1-null mutants, intracellular accumulation of dihydroxyacetone phosphate might be prevented if the cytosolic NADH generated...

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Bibliographic Details
Main Authors: Overkamp, Karin M., Bakker, Barbara M., Kötter, Peter, Luttik, Marijke A. H., van Dijken, Johannes P., Pronk, Jack T.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Physiology and Biotechnology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC123913/
https://ncbi.nlm.nih.gov/pubmed/12039737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.68.6.2814-2821.2002
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