Cofilin dysregulation alters actin turnover in frataxin-deficient neurons

Abnormalities in actin cytoskeleton have been linked to Friedreich’s ataxia (FRDA), an inherited peripheral neuropathy characterised by an early loss of neurons in dorsal root ganglia (DRG) among other clinical symptoms. Despite all efforts to date, we still do not fully understand the molecular eve...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Muñoz-Lasso, Diana C., Mollá, Belén, Calap-Quintana, Pablo, García-Giménez, José Luis, Pallardo, Federico V., Palau, Francesc, Gonzalez-Cabo, Pilar
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7090085/
https://ncbi.nlm.nih.gov/pubmed/32251310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-62050-7
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