Cofilin dysregulation alters actin turnover in frataxin-deficient neurons

Abnormalities in actin cytoskeleton have been linked to Friedreich’s ataxia (FRDA), an inherited peripheral neuropathy characterised by an early loss of neurons in dorsal root ganglia (DRG) among other clinical symptoms. Despite all efforts to date, we still do not fully understand the molecular eve...

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Foilsithe in:Sci Rep
Main Authors: Muñoz-Lasso, Diana C., Mollá, Belén, Calap-Quintana, Pablo, García-Giménez, José Luis, Pallardo, Federico V., Palau, Francesc, Gonzalez-Cabo, Pilar
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2020
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7090085/
https://ncbi.nlm.nih.gov/pubmed/32251310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-62050-7
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