Reversible Axonal Dystrophy by Calcium Modulation in Frataxin-Deficient Sensory Neurons of YG8R Mice

Friedreich’s ataxia (FRDA) is a peripheral neuropathy involving a loss of proprioceptive sensory neurons. Studies of biopsies from patients suggest that axonal dysfunction precedes the death of proprioceptive neurons in a dying-back process. We observed that the deficiency of frataxin in sensory neu...

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Bibliografske podrobnosti
izdano v:Front Mol Neurosci
Main Authors: Mollá, Belén, Muñoz-Lasso, Diana C., Riveiro, Fátima, Bolinches-Amorós, Arantxa, Pallardó, Federico V., Fernandez-Vilata, Angel, de la Iglesia-Vaya, María, Palau, Francesc, Gonzalez-Cabo, Pilar
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Neuroscience
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583981/
https://ncbi.nlm.nih.gov/pubmed/28912677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00264
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