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Differential role of planar cell polarity gene Vangl2 in embryonic and adult mammalian kidneys
Planar cell polarity (PCP) pathway is crucial for tissue morphogenesis. Mutations in PCP genes cause multi-organ anomalies including dysplastic kidneys. Defective PCP signaling was postulated to contribute to cystogenesis in polycystic kidney disease. This work was undertaken to elucidate the role o...
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| Publié dans: | PLoS One |
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| Auteurs principaux: | , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7089571/ https://ncbi.nlm.nih.gov/pubmed/32203543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0230586 |
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