The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation

The planar cell polarity (PCP) pathway, incorporating non-canonical Wnt signalling, controls embryonic convergent (CE) extension, polarized cell division and ciliary orientation. It also limits diameters of differentiating renal tubules, with mutation of certain components of the pathway causing cys...

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Main Authors: Yates, Laura L., Papakrivopoulou, Jenny, Long, David A., Goggolidou, Paraskevi, Connolly, John O., Woolf, Adrian S., Dean, Charlotte H.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2010
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972698/
https://ncbi.nlm.nih.gov/pubmed/20843830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq397
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