The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation

The planar cell polarity (PCP) pathway, incorporating non-canonical Wnt signalling, controls embryonic convergent (CE) extension, polarized cell division and ciliary orientation. It also limits diameters of differentiating renal tubules, with mutation of certain components of the pathway causing cys...

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Huvudupphovsmän: Yates, Laura L., Papakrivopoulou, Jenny, Long, David A., Goggolidou, Paraskevi, Connolly, John O., Woolf, Adrian S., Dean, Charlotte H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2010
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972698/
https://ncbi.nlm.nih.gov/pubmed/20843830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq397
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