Deficiency of the Planar Cell Polarity Protein Vangl2 in Podocytes Affects Glomerular Morphogenesis and Increases Susceptibility to Injury

The planar cell polarity (PCP) signaling pathway is crucial for tissue morphogenesis. Van Gogh-like protein 2 (Vangl2) is central in the PCP pathway; in mice, Vangl2 loss is embryonically lethal because of neural tube defects, and mutations in Vangl2 are associated with human neural tube defects. In...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Am Soc Nephrol
Egile Nagusiak: Rocque, Brittany L., Babayeva, Sima, Li, Jane, Leung, Vicki, Nezvitsky, Lisa, Cybulsky, Andrey V., Gros, Philippe, Torban, Elena
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Nephrology 2015
Gaiak:
Basic Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4341486/
https://ncbi.nlm.nih.gov/pubmed/25145929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014040340
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak