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The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation
The planar cell polarity (PCP) pathway, incorporating non-canonical Wnt signalling, controls embryonic convergent (CE) extension, polarized cell division and ciliary orientation. It also limits diameters of differentiating renal tubules, with mutation of certain components of the pathway causing cys...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2972698/ https://ncbi.nlm.nih.gov/pubmed/20843830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq397 |
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