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Conformational Transitions and the Activation of Heterotrimeric G Proteins by G Protein-Coupled Receptors

G protein-coupled receptors (GPCRs) are particularly attractive targets for therapeutic pharmaceuticals. This is because they are involved in almost all facets of physiology, in many pathophysiological processes, they are tractable due to their cell surface location, and can exhibit highly textured...

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Detalhes bibliográficos
Publicado no:ACS Pharmacol Transl Sci
Main Authors: Draper-Joyce, Christopher, Furness, Sebastian George Barton
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7088962/
https://ncbi.nlm.nih.gov/pubmed/32259062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.9b00054
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