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Conformational Transitions and the Activation of Heterotrimeric G Proteins by G Protein-Coupled Receptors

G protein-coupled receptors (GPCRs) are particularly attractive targets for therapeutic pharmaceuticals. This is because they are involved in almost all facets of physiology, in many pathophysiological processes, they are tractable due to their cell surface location, and can exhibit highly textured...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:ACS Pharmacol Transl Sci
Päätekijät: Draper-Joyce, Christopher, Furness, Sebastian George Barton
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2019
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7088962/
https://ncbi.nlm.nih.gov/pubmed/32259062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.9b00054
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