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Conformational Transitions and the Activation of Heterotrimeric G Proteins by G Protein-Coupled Receptors

G protein-coupled receptors (GPCRs) are particularly attractive targets for therapeutic pharmaceuticals. This is because they are involved in almost all facets of physiology, in many pathophysiological processes, they are tractable due to their cell surface location, and can exhibit highly textured...

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Vydáno v:ACS Pharmacol Transl Sci
Hlavní autoři: Draper-Joyce, Christopher, Furness, Sebastian George Barton
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2019
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7088962/
https://ncbi.nlm.nih.gov/pubmed/32259062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.9b00054
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