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Conformational dynamics of activation for the pentameric complex of dimeric G protein – coupled receptor and heterotrimeric G protein

Photoactivation of rhodopsin (Rho), a G protein-coupled receptor (GPCR), causes conformational changes that provide a specific binding site for the rod G protein, Gt. In this work we employed structural mass spectrometry (MS) techniques to elucidate the structural changes accompanying transition of...

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Detalhes bibliográficos
Main Authors: Orban, Tivadar, Jastrzebska, Beata, Gupta, Sayan, Wang, Benlian, Miyagi, Masaru, Chance, Mark R., Palczewski, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351692/
https://ncbi.nlm.nih.gov/pubmed/22579250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.03.017
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