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Substrate–Induced Changes in Dynamics of Rhodopsin Kinase (G Protein–Coupled Receptor Kinase 1)()
G protein–coupled receptor (GPCR) kinases (GRKs) instigate the desensitization of activated GPCRs via phosphorylation that promotes interaction with arrestins, thereby preventing the interaction of GPCRs with heterotrimeric G proteins. A current proposed model of GRK1 activation involves the binding...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3422436/ https://ncbi.nlm.nih.gov/pubmed/22480180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300295y |
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