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In vitro selection of ribozyme ligases that use prebiotically plausible 2-aminoimidazole–activated substrates
The hypothesized central role of RNA in the origin of life suggests that RNA propagation predated the advent of complex protein enzymes. A critical step of RNA replication is the template-directed synthesis of a complementary strand. Two experimental approaches have been extensively explored in the...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7084097/ https://ncbi.nlm.nih.gov/pubmed/32123094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1914367117 |
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