Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides

Despite evident regulatory roles of heparan sulfate (HS) saccharides in numerous biological processes, definitive information on the bioactive sequences of these polymers is lacking, with only a handful of natural structures sequenced to date. Here, we develop a “Shotgun” Ion Mobility Mass Spectrome...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Miller, Rebecca L., Guimond, Scott E., Schwörer, Ralf, Zubkova, Olga V., Tyler, Peter C., Xu, Yongmei, Liu, Jian, Chopra, Pradeep, Boons, Geert-Jan, Grabarics, Márkó, Manz, Christian, Hofmann, Johanna, Karlsson, Niclas G., Turnbull, Jeremy E., Struwe, Weston B., Pagel, Kevin
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083916/
https://ncbi.nlm.nih.gov/pubmed/32198425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15284-y
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