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The 3-O-sulfation of heparan sulfate modulates protein binding and lyase degradation
Humans express seven heparan sulfate (HS) 3-O-sulfotransferases that differ in substrate specificity and tissue expression. Although genetic studies have indicated that 3-O-sulfated HS modulates many biological processes, ligand requirements for proteins engaging with HS modified by 3-O-sulfate (3-O...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7826381/ https://ncbi.nlm.nih.gov/pubmed/33441484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2012935118 |
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