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Improved De Novo Sequencing of Heparin/Heparan Sulfate Oligosaccharides by Propionylation of Sites of Sulfation

The structure of heparin and heparan sulfate (Hep/HS) oligosaccharides, as determined by the length and the pattern of sulfation, acetylation, and uronic acid epimerization, dictates their biological function through modulating interactions with protein targets. But fine structural determination is...

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Détails bibliographiques
Publié dans:Carbohydr Res
Auteurs principaux: Liang, Quntao, Chopra, Pradeep, Boons, Geert-Jan, Sharp, Joshua S.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286702/
https://ncbi.nlm.nih.gov/pubmed/29920400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2018.06.002
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