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Improved De Novo Sequencing of Heparin/Heparan Sulfate Oligosaccharides by Propionylation of Sites of Sulfation

The structure of heparin and heparan sulfate (Hep/HS) oligosaccharides, as determined by the length and the pattern of sulfation, acetylation, and uronic acid epimerization, dictates their biological function through modulating interactions with protein targets. But fine structural determination is...

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Foilsithe in:Carbohydr Res
Main Authors: Liang, Quntao, Chopra, Pradeep, Boons, Geert-Jan, Sharp, Joshua S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286702/
https://ncbi.nlm.nih.gov/pubmed/29920400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2018.06.002
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