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The orexin-1 receptor antagonist SB-334867 reduces motivation, but not inhibitory control, in a rat stop signal task

There is considerable clinical interest in the neuropeptide orexin/hypocretin for its ability to regulate motivation and reward as well as arousal and wakefulness. For instance, antagonists for the orexin-1 receptor (OxR1) are thought to hold great promise for treating drug addiction and disorders a...

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Detalhes bibliográficos
Publicado no:Brain Res
Main Authors: Wiskerke, Joost, James, Morgan H., Aston-Jones, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083200/
https://ncbi.nlm.nih.gov/pubmed/31002819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2019.04.017
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