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The Orexin-1 Receptor Antagonist SB-334867 Reduces Alcohol Relapse Drinking, but not Alcohol-Seeking, in Alcohol-Preferring (P) Rats

PRINCIPLE: The orexin system has been hypothesized to regulate drug-seeking and drug self-administration behaviors, including ethanol (EtOH) seeking and consumption. However, studies on the effects of orexin receptor antagonists have not been conducted on robust alcohol-relapse behavior. OBJECTIVES:...

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Detalhes bibliográficos
Main Authors: Dhaher, Ronnie, Hauser, Sheketha R., Getachew, Bruk, Bell, Richard L., McBride, William J., McKinzie, David L., Rodd, Zachary A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943642/
https://ncbi.nlm.nih.gov/pubmed/20871792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ADM.0b013e3181bd893f
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