The Orexin-1 Antagonist SB-334867 Blocks Antipsychotic Treatment–Emergent Catalepsy: Implications for the Treatment of Extrapyramidal Symptoms

We have previously shown that the orexin-1 antagonist SB-334867 blocks the electrophysiological effects of haloperidol and olanzapine on the activity of A9 and A10 dopamine neurons. To evaluate if orexin-1 antagonists might block other effects of antipsychotic drugs in animals, we examined the effec...

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Hlavní autoři: Rasmussen, Kurt, Hsu, Mei-Ann, Noone, Stephen, Johnson, Bryan G., Thompson, Linda K., Hemrick-Luecke, Susan K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2007
Témata:
Theme: The Orexins/Hypocretins and Schizophrenia Ariel Y. Deutch
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779883/
https://ncbi.nlm.nih.gov/pubmed/17660489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbm087
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