Pharmacologic Blockade of 15-PGDH Protects Against Acute Renal Injury Induced by LPS in Mice

Prostaglandin pathway plays multiple roles in various physiological and pathological conditions. The present study aimed to investigate the effect of 15-hydroxyprostaglandin dehydrogenase (15-PGDH), a key enzyme in the degradation of prostaglandins, on lipopolysaccharide (LPS)-induced acute kidney i...

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Veröffentlicht in:Front Physiol
Hauptverfasser: Miao, Shuying, Lv, Caihong, Liu, Ying, Zhao, Jie, Li, Ting, Wang, Chunjiang, Xu, Yunfei, Wang, Xiaoli, Xiao, Xianzhong, Zhang, Huali
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Physiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7082810/
https://ncbi.nlm.nih.gov/pubmed/32231583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00138
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