Pharmacologic Blockade of 15-PGDH Protects Against Acute Renal Injury Induced by LPS in Mice

Prostaglandin pathway plays multiple roles in various physiological and pathological conditions. The present study aimed to investigate the effect of 15-hydroxyprostaglandin dehydrogenase (15-PGDH), a key enzyme in the degradation of prostaglandins, on lipopolysaccharide (LPS)-induced acute kidney i...

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Detalles Bibliográficos
Publicado en:Front Physiol
Main Authors: Miao, Shuying, Lv, Caihong, Liu, Ying, Zhao, Jie, Li, Ting, Wang, Chunjiang, Xu, Yunfei, Wang, Xiaoli, Xiao, Xianzhong, Zhang, Huali
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Physiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7082810/
https://ncbi.nlm.nih.gov/pubmed/32231583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00138
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