15-hydroxyprostaglandin dehydrogenase (15-PGDH) prevents lipopolysaccharide (LPS)-induced acute liver injury

The NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) catalyzes the oxidation of the 15(S)-hydroxyl group of prostaglandin E(2) (PGE(2)), converting the pro-inflammatory PGE(2) to the anti-inflammatory 15-keto-PGE(2) (an endogenous ligand for peroxisome proliferator-activated receptor-g...

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Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Yao, Lu, Chen, Weina, Song, Kyoungsub, Han, Chang, Gandhi, Chandrashekhar R., Lim, Kyu, Wu, Tong
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397067/
https://ncbi.nlm.nih.gov/pubmed/28423012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176106
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