Pharmacologic Blockade of 15-PGDH Protects Against Acute Renal Injury Induced by LPS in Mice

Prostaglandin pathway plays multiple roles in various physiological and pathological conditions. The present study aimed to investigate the effect of 15-hydroxyprostaglandin dehydrogenase (15-PGDH), a key enzyme in the degradation of prostaglandins, on lipopolysaccharide (LPS)-induced acute kidney i...

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Publicat a:Front Physiol
Autors principals: Miao, Shuying, Lv, Caihong, Liu, Ying, Zhao, Jie, Li, Ting, Wang, Chunjiang, Xu, Yunfei, Wang, Xiaoli, Xiao, Xianzhong, Zhang, Huali
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7082810/
https://ncbi.nlm.nih.gov/pubmed/32231583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00138
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