HIV-1 Vpu Downregulates Tim-3 from the Surface of Infected CD4(+) T Cells

Along with other immune checkpoints, T cell immunoglobulin and mucin domain-containing protein 3 (Tim-3) is expressed on exhausted CD4(+) and CD8(+) T cells and is upregulated on the surface of these cells upon infection by human immunodeficiency virus type 1 (HIV-1). Recent reports have suggested a...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Prévost, Jérémie, Edgar, Cassandra R., Richard, Jonathan, Trothen, Steven M., Jacob, Rajesh Abraham, Mumby, Mitchell J., Pickering, Suzanne, Dubé, Mathieu, Kaufmann, Daniel E., Kirchhoff, Frank, Neil, Stuart J. D., Finzi, Andrés, Dikeakos, Jimmy D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2020
Teme:
Virus-Cell Interactions
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081912/
https://ncbi.nlm.nih.gov/pubmed/31941771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01999-19
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