Development of a CRISPR-SaCas9 system for projection- and function-specific gene editing in the rat brain

A genome editing technique based on the clustered regularly interspaced short palindromic repeats (CRISPR)–associated endonuclease Cas9 enables efficient modification of genes in various cell types, including neurons. However, neuronal ensembles even in the same brain region are not anatomically or...

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Dades bibliogràfiques
Publicat a:Sci Adv
Autors principals: Sun, Haojie, Fu, Su, Cui, Shuang, Yin, Xiangsha, Sun, Xiaoyan, Qi, Xuetao, Cui, Kun, Wang, Jiaxin, Ma, Longyu, Liu, Feng-Yu, Liao, Fei-Fei, Wang, Xin-Hong, Yi, Ming, Wan, You
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2020
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080442/
https://ncbi.nlm.nih.gov/pubmed/32206715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay6687
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