Development of a CRISPR-SaCas9 system for projection- and function-specific gene editing in the rat brain

A genome editing technique based on the clustered regularly interspaced short palindromic repeats (CRISPR)–associated endonuclease Cas9 enables efficient modification of genes in various cell types, including neurons. However, neuronal ensembles even in the same brain region are not anatomically or...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Sun, Haojie, Fu, Su, Cui, Shuang, Yin, Xiangsha, Sun, Xiaoyan, Qi, Xuetao, Cui, Kun, Wang, Jiaxin, Ma, Longyu, Liu, Feng-Yu, Liao, Fei-Fei, Wang, Xin-Hong, Yi, Ming, Wan, You
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080442/
https://ncbi.nlm.nih.gov/pubmed/32206715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay6687
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