Inhibition of HBV Expression in HBV Transgenic Mice Using AAV-Delivered CRISPR-SaCas9

The chronic production of hepatitis B viral (HBV) antigens could cause inflammation and necrosis, leading to elevation of liver enzymes from necrotic hepatocytes, hepatitis, cirrhosis, hepatocellular carcinoma, and liver failure. However, no current treatment is capable of significantly reducing HBs...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Immunol
Päätekijät: Li, Hao, Sheng, Chunyu, Liu, Hongbo, Wang, Shan, Zhao, Jiangyun, Yang, Lang, Jia, Leili, Li, Peng, Wang, Ligui, Xie, Jing, Xu, Dongping, Sun, Yansong, Qiu, Shaofu, Song, Hongbin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2018
Aiheet:
Immunology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141737/
https://ncbi.nlm.nih.gov/pubmed/30254645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02080
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