Influence of cytoskeleton organization on recombinant protein expression by CHO cells

In this study, we assessed the importance of cytoskeleton organization in the mammalian cells used to produce therapeutic proteins. Two cytoskeletal genes, Actin alpha cardiac muscle 1 (ACTC1) and a guanosine triphosphate GTPase‐activating protein (TAGAP), were found to be upregulated in highly prod...

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Detaylı Bibliyografya
Yayımlandı:Biotechnol Bioeng
Asıl Yazarlar: Pourcel, Lucille, Buron, Flavien, Arib, Ghislaine, Le Fourn, Valérie, Regamey, Alexandre, Bodenmann, Iris, Girod, Pierre‐Alain, Mermod, Nicolas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2020
Konular:
ARTICLES
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7079171/
https://ncbi.nlm.nih.gov/pubmed/31956990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.27277
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