High performance CHO cell line development platform for enhanced production of recombinant proteins including difficult-to-express proteins

Por Girod, Pierre-Alain, Le Fourn, Valérie, Calabrese, David, Regamey, Alexandre, Ley, Deborah, Mermod, Nicolas
Publicado em 2013

High-level transgene expression by homologous recombination-mediated gene transfer

Por Grandjean, Mélanie, Girod, Pierre-Alain, Calabrese, David, Kostyrko, Kaja, Wicht, Marianne, Yerly, Florence, Mazza, Christian, Beckmann, Jacques S., Martinet, Danielle, Mermod, Nicolas
Publicado em 2011

MAR Elements and Transposons for Improved Transgene Integration and Expression

Por Ley, Déborah, Harraghy, Niamh, Le Fourn, Valérie, Bire, Solenne, Girod, Pierre-Alain, Regamey, Alexandre, Rouleux-Bonnin, Florence, Bigot, Yves, Mermod, Nicolas
Publicado em 2013

MAR‐Mediated transgene integration into permissive chromatin and increased expression by recombination pathway engineering

Por Kostyrko, Kaja, Neuenschwander, Samuel, Junier, Thomas, Regamey, Alexandre, Iseli, Christian, Schmid‐Siegert, Emanuel, Bosshard, Sandra, Majocchi, Stefano, Le Fourn, Valérie, Girod, Pierre‐Alain, Xenarios, Ioannis, Mermod, Nicolas
Publicado no Biotechnol Bioeng (2016)

Improving biophysical properties of a bispecific antibody scaffold to aid developability: Quality by molecular design

Por Von Kreudenstein, Thomas Spreter, Escobar-Carbrera, Eric, Lario, Paula I., D’Angelo, Igor, Brault, Karine, Kelly, John F, Durocher, Yves, Baardsnes, Jason, Woods, R. Jeremy, Xie, Michael Hongwei, Girod, Pierre-Alain, Suits, Michael D. L., Boulanger, Martin J., Poon, David K. Y., Ng, Gordon Y., Dixit, Surjit B.
Publicado em 2013