High-level transgene expression by homologous recombination-mediated gene transfer

Gene transfer and expression in eukaryotes is often limited by a number of stably maintained gene copies and by epigenetic silencing effects. Silencing may be limited by the use of epigenetic regulatory sequences such as matrix attachment regions (MAR). Here, we show that successive transfections of...

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Bibliografiske detaljer
Main Authors: Grandjean, Mélanie, Girod, Pierre-Alain, Calabrese, David, Kostyrko, Kaja, Wicht, Marianne, Yerly, Florence, Mazza, Christian, Beckmann, Jacques S., Martinet, Danielle, Mermod, Nicolas
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Methods Online
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159483/
https://ncbi.nlm.nih.gov/pubmed/21652640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr436
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