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Gating mechanism of hyperpolarization-activated HCN pacemaker channels

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are essential for rhythmic activity in the heart and brain, and mutations in HCN channels are linked to heart arrhythmia and epilepsy. HCN channels belong to the family of voltage-gated K(+) (Kv) channels. However, why HCN channels a...

詳細記述

保存先:
書誌詳細
出版年:Nat Commun
主要な著者: Ramentol, Rosamary, Perez, Marta E., Larsson, H. Peter
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7078272/
https://ncbi.nlm.nih.gov/pubmed/32184399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15233-9
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