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Src Tyrosine Kinase Alters Gating of Hyperpolarization-Activated HCN4 Pacemaker Channel through Tyr(531)
We recently discovered that the constitutively active Src tyrosine kinase can enhance the HCN4 channel activity by binding to the channel protein. To investigate the mechanism of modulation by Src of HCN channels, we studied the effects of a selective inhibitor of Src tyrosine kinase, PP2, on HCN4 a...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2784909/ https://ncbi.nlm.nih.gov/pubmed/17977941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00236.2007 |
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