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Constitutively Active Src Tyrosine Kinase Changes Gating of HCN4 Channels Through Direct Binding to the Channel Proteins
Cardiac pacemaker current, i(f), is generated by hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. Our previous studies demonstrated that altered tyrosine phosphorylation can modulate the properties of both i(f) and HCN channels. To assess a hypothesis that the intracellular tyrosi...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1693968/ https://ncbi.nlm.nih.gov/pubmed/16680072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.fjc.0000211740.47960.8b |
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