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Colonic inflammation alters Src kinase-dependent gating properties of single Ca(2+) channels via tyrosine nitration

Nitration of L-type calcium channels during colonic inflammation impairs phosphorylation by the tyrosine kinase, Src kinase. This results in decreased calcium currents. The purpose of this study was to determine the mechanism of the downregulation of Ca(2+) currents in colonic inflammation. In whole...

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書目詳細資料
Main Authors: Ross, Gracious R., Kang, Minho, Akbarali, Hamid I.
格式: Artigo
語言:Inglês
出版: American Physiological Society 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061627/
https://ncbi.nlm.nih.gov/pubmed/20378833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00056.2010
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