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Colonic inflammation alters Src kinase-dependent gating properties of single Ca(2+) channels via tyrosine nitration
Nitration of L-type calcium channels during colonic inflammation impairs phosphorylation by the tyrosine kinase, Src kinase. This results in decreased calcium currents. The purpose of this study was to determine the mechanism of the downregulation of Ca(2+) currents in colonic inflammation. In whole...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3061627/ https://ncbi.nlm.nih.gov/pubmed/20378833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00056.2010 |
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