eIF1 discriminates against suboptimal initiation sites to prevent excessive uORF translation genome-wide

The translation preinitiation complex (PIC) scans the mRNA for an AUG codon in a favorable context. Previous findings suggest that the factor eIF1 discriminates against non-AUG start codons by impeding full accommodation of Met-tRNA(i) in the P site of the 40S ribosomal subunit, necessitating eIF1 d...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:RNA
Asıl Yazarlar: Zhou, Fujun, Zhang, Hongen, Kulkarni, Shardul D., Lorsch, Jon R., Hinnebusch, Alan G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7075259/
https://ncbi.nlm.nih.gov/pubmed/31915290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.073536.119
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller