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Temperature-dependent regulation of upstream open reading frame translation in S. cerevisiae

BACKGROUND: Translation of an mRNA in eukaryotes starts at an AUG codon in most cases, but near-cognate codons (NCCs) such as UUG, ACG, and AUU can also be used as start sites at low levels in Saccharomyces cerevisiae. Initiation from NCCs or AUGs in the 5′-untranslated regions (UTRs) of mRNAs can l...

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Detalhes bibliográficos
Publicado no:BMC Biol
Main Authors: Kulkarni, Shardul D., Zhou, Fujun, Sen, Neelam Dabas, Zhang, Hongen, Hinnebusch, Alan G., Lorsch, Jon R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6898956/
https://ncbi.nlm.nih.gov/pubmed/31810458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-019-0718-5
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