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Adverse effects of BMPR2 suppression in macrophages in animal models of pulmonary hypertension

Inflammatory cells contribute to irreversible damage in pulmonary arterial hypertension (PAH). We hypothesized that in PAH, dysfunctional BMPR2 signaling in macrophages contributes to pulmonary vascular injury and phenotypic changes via proinflammatory cytokine production. Studies were conducted in:...

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Podrobná bibliografie
Vydáno v:Pulm Circ
Hlavní autoři: West, James, Chen, Xinping, Yan, Ling, Gladson, Santhi, Loyd, James, Rizwan, Hamid, Talati, Megha
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7074495/
https://ncbi.nlm.nih.gov/pubmed/31124398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894019856483
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