Cytoskeletal defects in Bmpr2-associated pulmonary arterial hypertension

The heritable form of pulmonary arterial hypertension (PAH) is typically caused by a mutation in bone morphogenic protein receptor type 2 (BMPR2), and mice expressing Bmpr2 mutations develop PAH with features similar to human disease. BMPR2 is known to interact with the cytoskeleton, and human array...

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Bibliografiske detaljer
Main Authors: Johnson, Jennifer A., Hemnes, Anna R., Perrien, Daniel S., Schuster, Manfred, Robinson, Linda J., Gladson, Santhi, Loibner, Hans, Bai, Susan, Blackwell, Tom R., Tada, Yuji, Harral, Julie W., Talati, Megha, Lane, Kirk B., Fagan, Karen A., West, James
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2012
Fag:
Editorial Focus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311512/
https://ncbi.nlm.nih.gov/pubmed/22180660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00202.2011
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