Mice expressing BMPR2(R899X) transgene in smooth muscle develop pulmonary vascular lesions

Familial pulmonary arterial hypertension (PAH) is associated with mutations in bone morphogenetic protein type II receptor (BMPR2). Many of these mutations occur in the BMPR2 tail domain, leaving the SMAD functions intact. To determine the in vivo consequences of BMPR2 tail domain mutation, we creat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: West, James, Harral, Julie, Lane, Kirk, Deng, Yupu, Ickes, Brian, Crona, Daniel, Albu, Sebastian, Stewart, Duncan, Fagan, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584890/
https://ncbi.nlm.nih.gov/pubmed/18723761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90255.2008
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados