Cytoskeletal defects in Bmpr2-associated pulmonary arterial hypertension

The heritable form of pulmonary arterial hypertension (PAH) is typically caused by a mutation in bone morphogenic protein receptor type 2 (BMPR2), and mice expressing Bmpr2 mutations develop PAH with features similar to human disease. BMPR2 is known to interact with the cytoskeleton, and human array...

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Main Authors: Johnson, Jennifer A., Hemnes, Anna R., Perrien, Daniel S., Schuster, Manfred, Robinson, Linda J., Gladson, Santhi, Loibner, Hans, Bai, Susan, Blackwell, Tom R., Tada, Yuji, Harral, Julie W., Talati, Megha, Lane, Kirk B., Fagan, Karen A., West, James
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2012
Teme:
Editorial Focus
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311512/
https://ncbi.nlm.nih.gov/pubmed/22180660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00202.2011
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