BMPR2 mutation alters the lung macrophage endothelin-1 cascade in a mouse model and patients with heritable pulmonary artery hypertension

Macrophage derived-endothelin-1 (ET-1) has been suggested to contribute to a number of chronic lung diseases. Whether the ET-1 cascade from non-vascular sources (inflammatory cells) also contributes to pulmonary artery hypertension (PAH) and in particular to heritable PAH (HPAH) with known bone morp...

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Bibliographic Details
Main Authors: Talati, M., West, J., Blackwell, T. R., Loyd, J. E., Meyrick, B.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2010
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951074/
https://ncbi.nlm.nih.gov/pubmed/20562228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00295.2009
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