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Altered Expression and Signal Transduction of Endothelin-1 Receptors in Heritable and Idiopathic Pulmonary Arterial Hypertension

Human pulmonary arterial smooth muscle cells (PASMC) were isolated from elastic pulmonary arteries dissected from lungs of individuals with and without pulmonary arterial hypertension (PAH). Reflecting increased smooth muscle constriction in cells from PAH subject, Ca(2+) influx in response to endot...

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Autori principali: Yu, Jun, Taylor, Linda, Wilson, Jamie, Comhair, Suzy, Erzurum, Serpil, Polgar, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496420/
https://ncbi.nlm.nih.gov/pubmed/22688668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24132
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