High levels of hyaluronan in idiopathic pulmonary arterial hypertension

Hyaluronan (HA), a large glycosaminoglycan found in the ECM, has major roles in lung and vascular biology and disease. However, its role in idiopathic pulmonary arterial hypertension (IPAH) is unknown. We hypothesized that HA metabolism is abnormal in IPAH. We measured the plasma levels of HA in IPA...

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Detalhes bibliográficos
Main Authors: Aytekin, Metin, Comhair, Suzy A. A., de la Motte, Carol, Bandyopadhyay, Sudip K., Farver, Carol F., Hascall, Vincent C., Erzurum, Serpil C., Dweik, Raed A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584887/
https://ncbi.nlm.nih.gov/pubmed/18776053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90306.2008
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