High levels of hyaluronan in idiopathic pulmonary arterial hypertension

Hyaluronan (HA), a large glycosaminoglycan found in the ECM, has major roles in lung and vascular biology and disease. However, its role in idiopathic pulmonary arterial hypertension (IPAH) is unknown. We hypothesized that HA metabolism is abnormal in IPAH. We measured the plasma levels of HA in IPA...

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Autors principals: Aytekin, Metin, Comhair, Suzy A. A., de la Motte, Carol, Bandyopadhyay, Sudip K., Farver, Carol F., Hascall, Vincent C., Erzurum, Serpil C., Dweik, Raed A.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2008
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584887/
https://ncbi.nlm.nih.gov/pubmed/18776053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90306.2008
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