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Hyaluronan and Its Heavy Chain Modification in Asthma Severity and Experimental Asthma Exacerbation
Hyaluronan (HA) is a large (>1500 kDa) polysaccharide of the extracellular matrix that has been linked to severity and inflammation in asthma. During inflammation, HA becomes covalently modified with heavy chains (HC-HA) from inter-α-inhibitor (IαI), which functions to increase its avidity for le...
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| 發表在: | J Biol Chem |
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| Main Authors: | , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4645592/ https://ncbi.nlm.nih.gov/pubmed/26209637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.663823 |
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