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Adverse effects of BMPR2 suppression in macrophages in animal models of pulmonary hypertension

Inflammatory cells contribute to irreversible damage in pulmonary arterial hypertension (PAH). We hypothesized that in PAH, dysfunctional BMPR2 signaling in macrophages contributes to pulmonary vascular injury and phenotypic changes via proinflammatory cytokine production. Studies were conducted in:...

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Detalhes bibliográficos
Publicado no:Pulm Circ
Main Authors: West, James, Chen, Xinping, Yan, Ling, Gladson, Santhi, Loyd, James, Rizwan, Hamid, Talati, Megha
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7074495/
https://ncbi.nlm.nih.gov/pubmed/31124398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894019856483
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