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An Alkyne-functionalized Arginine for Solid-Phase Synthesis Enabling “Bioorthogonal” Peptide Conjugation
[Image: see text] Lately, amino-functionalized N(ω)-carbamoylated arginines were introduced as arginine surrogates enabling peptide labeling. However, this approach is hardly compatible with peptides also containing lysine or cysteine. Here, we present the synthesis of an alkyne-functionalized, N(ω)...
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| 發表在: | ACS Med Chem Lett |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Chemical
Society
2019
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| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7073887/ https://ncbi.nlm.nih.gov/pubmed/32184966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00388 |
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