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Modifications at Arg and Ile Give Neurotensin(8–13) Derivatives with High Stability and Retained NTS(1) Receptor Affinity

[Image: see text] Due to its expression in various malignant tumors, the neurotensin receptor 1 (NTS(1)R) has been suggested and explored as a target for tumor diagnosis and therapy. Animal model-based investigations of various radiolabeled NTS(1)R ligands derived from the hexapeptide neurotensin(8–...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Schindler, Lisa, Bernhardt, Günther, Keller, Max
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580558/
https://ncbi.nlm.nih.gov/pubmed/31223455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00122
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