Neurotensin(8-13) analogs targeting NTS1 and NTS2 receptors: A comparative in vitro and molecular modeling study

The simultaneous activation of both neurotensin type 1 and 2 receptors (NTS1R and NTS2R) through the neuronal peptide neurotensin (NT), activating the dopamine (DA) release and DA signaling within the dopaminergic system in the brain, suggest that NTS1R/NTS2R dual-specific NT analogs may represent a...

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मुख्य लेखकों:	Kiril Kirilov, Maria Ponticelli, Toni Kühl, Harald Hübner, Maya G. Georgieva, Matthias Vogel, Aneliya A. Balacheva, Bodo Haas, Tamara I. Pajpanova, Maima Matin, Luigi Milella, Peter Gmeiner, Diana Imhof, Nikolay T. Tzvetkov
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Elsevier 2025-01-01
श्रृंखला:	Current Research in Biotechnology
विषय:	In vitro studies Neurotensin Neurotensin receptors Molecular Modeling MD simulation
ऑनलाइन पहुंच:	http://www.sciencedirect.com/science/article/pii/S2590262825000292
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